Sildenafil is an erectile dysfunction medicine available as an oral tablet. The active element in Kamagra is sildenafil. Sildenafil promotes erections by acting as a vasodilator. It works by inhibiting phosphodiesterase 5, which causes cGMP levels to rise, causing smooth muscles in capillaries to relax and dilate. Sexual excitement promotes erection as a result.

To have the most effect, the medicine should be taken on an empty stomach within 60 minutes of engaging in sexual activity. Sildenafil’s effects last for four to six hours on an average. Sildenafil is usually taken once a day at a dose of 50 mg. If the regular dose is insufficient, they can be increased to 100 mg, or reduced to 25 mg if moderate adverse effects arise.

Side Effects:

All vasodilators have almost identical side effects. These are some of Sildenafil’s side effects:




Vidalista contains the active component tadalafil. Tadalafil increases blood flow in the penis by inhibiting phosphodiesterase 5, which prevents cGMP from being degraded. When phosphodiesterase 5 is suppressed, cGMP levels increase, causing the smooth muscle of blood vessels to relax and dilate.

Tadalafil is an oral medicine with a 30-minute onset of action. The most appealing aspect of this medication is that it lasts for about 36 hours, with only one dose prolonging nearly two days.

Side Effects:

Some of Tadalafil’s bad side effects are listed below:


Tadalafil and Sildenafil are two of the most popular and prescribed ED medicines for erectile dysfunction and impotence. Since 1998, everyone has been aware of these medications, and many doctors use them to treat ED patients. Both of these medications are available in a variety of dosages based on the degree of erectile dysfunction. These drugs result in a nearly 90% recovery rate. Although the start and duration of action of various medications varied, the adverse effects are nearly the same and have the same nature against a variety of pharmaceuticals, i.e. similar drug interactions. SILDENAFIL AND TADALAFIL do not treat low sexual desire. They just facilitate the normal erection mechanisms in your body. If one is not stimulated, consuming them daily is not going to help.

Even though these medications have a lot in common, they should not be taken together. Tadalafil and Sildenafil should not be taken combined to treat erectile dysfunction (ED). Many patients believe that taking them in combination will improve their performance and recovery, however, this is a ridiculous idea. These ED drugs are only effective if you’re sexually active. It’s also common advice to take one or another right before intercourse, but not on a daily or regular basis. Combining both is essentially the same as boosting your entire PDE5 inhibitor prescription. Boosting your medicine dose without consulting the physician can be risky. A larger dose of medications wouldn’t have the same impact on the body as a smaller dose.

These medications were undoubtedly taken in combination a few years ago. It was suggested that modest doses be given in conjunction. In severe cases of erectile dysfunction, 5 mg of Tadalafil and 50 mg of Sildenafil were given, with recovery and improved performance. The legal limit for each substance is 100 milligrams. However, it is no longer acceptable or recommended to prescribe ED drugs in combination, especially at larger doses. Both these medicines have substantial negative effects when taken in higher doses. The plasma concentrations in the bloodstream grow as the drug dose is increased. As a result, if a high dose of Tadalafil and Sildenafil is utilized, the combination may not be effective. Tadalafil and sildenafil must not be used together. Taking multiple ED treatments simultaneously results in undesirable and sometimes severe side effects. A high dose of the medicine might produce a severe fall in blood pressure, which can lead to cardiac arrest. As a result, before taking something that could be dangerous to the health, one must consider any complex correlations with the physician.


Erectile dysfunction drugs such as sildenafil and tadalafil have possible effects on ED treatment. They both work by inhibiting phosphodiesterase 5, which prevents the degradation of cGMP. When phosphodiesterase 5 is inhibited, cGMP levels rise, leading blood vessel smooth muscle to relax and dilate, as well as headaches, nausea, dizziness, indigestion, and visual disturbances.

To treat erectile dysfunction, Tadalafil and Sildenafil should not be taken together (ED). Several patients believe that combining them will enable them perform much better and recover more quickly. Taking various ED medications at the same time has unfavorable and occasionally severe adverse effects. A high dose of the drug could cause a dangerous drop in blood pressure, which could result in cardiac arrest. Taking ED medications in combination without contacting a doctor almost invariably results in serious side effects. If you take more than 100mg of any ED medication, side effects begin to occur, and mixing two medications that are equivalent to more than 100mg will land you in the emergency department.

Both of them use the same method. It is not suggested to take Tadalafil for 24 hours after taking a dose of Sildenafil for ED. Alternatively, if one is taking Tadalafil, one should not consume Sildenafil for the next 36 hours. In summary, it is not a good idea to combine Tadalafil and Sildenafil throughout their active periods. Read more about choosing between Sildenafil or Tadalafil on our website


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